Human

Human Kidney Gene DataBase
Name serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Symbol SERPINE1
Aliases PAI; PAI1; PAI-1; PLANH1; plasminogen activator inhibitor, type I
Gene Product
  • plasminogen activator inhibitor-1
Category
UniGene Hs.414795 
Reference Sequence
mRNA: NM_000602 Protein: NP_000593
OMIM and SNP
OMIM: 173360 SNP: NCBI SNP
Locus
LocusLink: 5054Chromosome: 7Cytoband: 7q21.3-q22 UCSC Genome Map Eesembl Genome Map
Gene Ontology
Expression
EST (784 ESTs, 178 libraries)
Tissue Breadth ? CPM ?
adiposeBreadth of expression: 1 out of 8 libraries express this gene (12.50%)Average CPM:1.31
boneBreadth of expression: 13 out of 24 libraries express this gene (54.17%)Average CPM:0.30
brainBreadth of expression: 5 out of 759 libraries express this gene (0.66%)Average CPM:0.80
cartilageBreadth of expression: 6 out of 16 libraries express this gene (37.50%)Average CPM:0.42
cervixBreadth of expression: 2 out of 11 libraries express this gene (18.18%)Average CPM:0.13
colonBreadth of expression: 9 out of 930 libraries express this gene (0.97%)Average CPM:0.36
esophagusBreadth of expression: 1 out of 8 libraries express this gene (12.50%)Average CPM:0.46
eyeBreadth of expression: 1 out of 24 libraries express this gene (4.17%)Average CPM:0.13
head and neckBreadth of expression: 3 out of 680 libraries express this gene (0.44%)Average CPM:4.69
heartBreadth of expression: 1 out of 26 libraries express this gene (3.85%)Average CPM:0.03
kidneyBreadth of expression: 6 out of 145 libraries express this gene (4.14%)Average CPM:0.52
liverBreadth of expression: 7 out of 65 libraries express this gene (10.77%)Average CPM:2.16
lungBreadth of expression: 14 out of 334 libraries express this gene (4.19%)Average CPM:1.78
lymph nodeBreadth of expression: 1 out of 22 libraries express this gene (4.55%)Average CPM:3.06
mammary glandBreadth of expression: 3 out of 1038 libraries express this gene (0.29%)Average CPM:0.35
muscleBreadth of expression: 1 out of 83 libraries express this gene (1.20%)Average CPM:0.48
nervousBreadth of expression: 4 out of 21 libraries express this gene (19.05%)Average CPM:0.26
ovaryBreadth of expression: 4 out of 170 libraries express this gene (2.35%)Average CPM:1.61
pancreasBreadth of expression: 4 out of 20 libraries express this gene (20.00%)Average CPM:2.14
placentaBreadth of expression: 28 out of 358 libraries express this gene (7.82%)Average CPM:5.26
prostateBreadth of expression: 1 out of 309 libraries express this gene (0.32%)Average CPM:0.80
skinBreadth of expression: 6 out of 38 libraries express this gene (15.79%)Average CPM:0.47
stomachBreadth of expression: 2 out of 310 libraries express this gene (0.65%)Average CPM:0.65
testisBreadth of expression: 1 out of 180 libraries express this gene (0.56%)Average CPM:0.07
thymusBreadth of expression: 2 out of 23 libraries express this gene (8.70%)Average CPM:1.73
thyroidBreadth of expression: 1 out of 48 libraries express this gene (2.08%)Average CPM:70.86
uncharacterized tissueBreadth of expression: 36 out of 1739 libraries express this gene (2.07%)Average CPM:0.65
uterusBreadth of expression: 4 out of 236 libraries express this gene (1.69%)Average CPM:0.12
vascularBreadth of expression: 5 out of 18 libraries express this gene (27.78%)Average CPM:6.57
EvidencePolymorphism in Lupus Nephritis

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco