Human

Human Kidney Gene DataBase
Name Fraser syndrome 1
Symbol FRAS1
Aliases FLJ14927; FLJ22031; KIAA1500; extracellular matrix protein
Gene Product
  • Fraser syndrome 1 isoform 4
  • Fraser syndrome 1 isoform 1
  • Fraser syndrome 1 isoform 2
  • Fraser syndrome 1 isoform 3
Category
UniGene Hs.15420 
Reference Sequence
mRNA: NM_206841 Protein: NP_996672
OMIM and SNP
OMIM: 607830 SNP: NCBI SNP
Locus
LocusLink: 80144Chromosome: 4Cytoband: 4q21.21 UCSC Genome Map Eesembl Genome Map
SummaryThe FRAS1 gene encodes a putative extracellular matrix (ECM) protein and is mutated in Fraser syndrome (MIM 219000) (McGregor et al., 2003 [PubMed 12766769]).[supplied by OMIM]
Expression
EST (130 ESTs, 63 libraries)
Tissue Breadth ? CPM ?
boneBreadth of expression: 1 out of 24 libraries express this gene (4.17%)Average CPM:1.52
brainBreadth of expression: 9 out of 759 libraries express this gene (1.19%)Average CPM:68.07
cartilageBreadth of expression: 1 out of 16 libraries express this gene (6.25%)Average CPM:1.47
colonBreadth of expression: 6 out of 930 libraries express this gene (0.65%)Average CPM:19.62
eyeBreadth of expression: 1 out of 24 libraries express this gene (4.17%)Average CPM:2.64
head and neckBreadth of expression: 1 out of 680 libraries express this gene (0.15%)Average CPM:101.21
heartBreadth of expression: 1 out of 26 libraries express this gene (3.85%)Average CPM:1.92
kidneyBreadth of expression: 2 out of 145 libraries express this gene (1.38%)Average CPM:0.80
liverBreadth of expression: 1 out of 65 libraries express this gene (1.54%)Average CPM:11.43
lungBreadth of expression: 10 out of 334 libraries express this gene (2.99%)Average CPM:31.40
mammary glandBreadth of expression: 1 out of 1038 libraries express this gene (0.10%)Average CPM:1.05
muscleBreadth of expression: 2 out of 83 libraries express this gene (2.41%)Average CPM:1.44
nervousBreadth of expression: 1 out of 21 libraries express this gene (4.76%)Average CPM:2.93
ovaryBreadth of expression: 1 out of 170 libraries express this gene (0.59%)Average CPM:1.25
placentaBreadth of expression: 6 out of 358 libraries express this gene (1.68%)Average CPM:2.53
skinBreadth of expression: 1 out of 38 libraries express this gene (2.63%)Average CPM:0.36
stomachBreadth of expression: 1 out of 310 libraries express this gene (0.32%)Average CPM:0.43
testisBreadth of expression: 1 out of 180 libraries express this gene (0.56%)Average CPM:0.18
uncharacterized tissueBreadth of expression: 8 out of 1739 libraries express this gene (0.46%)Average CPM:3.93
uterusBreadth of expression: 4 out of 236 libraries express this gene (1.69%)Average CPM:4.30
vascularBreadth of expression: 1 out of 18 libraries express this gene (5.56%)Average CPM:1.53
SAGE (5982267 tags, 111 libraries)
Tissue Breadth ? CPM ?
bloodBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:20.61
brainBreadth of expression: 19 out of 30 libraries express this gene (63.33%)Average CPM:30.08
cervixBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:65.75
colonBreadth of expression: 6 out of 8 libraries express this gene (75.00%)Average CPM:29.86
eyeBreadth of expression: 3 out of 6 libraries express this gene (50.00%)Average CPM:32.77
heartBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:47.42
kidneyBreadth of expression: 2 out of 3 libraries express this gene (66.67%)Average CPM:75.08
liverBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:44.87
lungBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:11.22
mammary glandBreadth of expression: 12 out of 20 libraries express this gene (60.00%)Average CPM:64.03
muscleBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:18.56
nervousBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:18.04
ovaryBreadth of expression: 3 out of 10 libraries express this gene (30.00%)Average CPM:38.01
pancreasBreadth of expression: 5 out of 8 libraries express this gene (62.50%)Average CPM:31.87
prostateBreadth of expression: 10 out of 14 libraries express this gene (71.43%)Average CPM:52.04
skinBreadth of expression: 4 out of 7 libraries express this gene (57.14%)Average CPM:109.83
stomachBreadth of expression: 3 out of 4 libraries express this gene (75.00%)Average CPM:30.28
uncharacterized tissueBreadth of expression: 12 out of 20 libraries express this gene (60.00%)Average CPM:33.35
vascularBreadth of expression: 2 out of 3 libraries express this gene (66.67%)Average CPM:15.18
EvidenceMutation in System Syndrom with Kidney Involvment

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco