Human

Human Kidney Gene DataBase
Name solute carrier family 4, sodium bicarbonate cotransporter, member 4
Symbol SLC4A4
Aliases KNBC; NBC1; NBC2; pNBC; HNBC1; hhNMC; SLC4A5; solute carrier family 4, sodium bicarbonate cotransporter, member 5; sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas)
Gene Product
  • solute carrier family 4, sodium bicarbonate cotransporter, member 4
Category
UniGene Hs.5462 
Reference Sequence
mRNA: NM_003759 Protein: NP_003750
OMIM and SNP
OMIM: 603345 SNP: NCBI SNP
Locus
LocusLink: 8671Chromosome: 4Cytoband: 4q21 UCSC Genome Map Eesembl Genome Map
Gene Ontology
Expression
EST (216 ESTs, 82 libraries)
Tissue Breadth ? CPM ?
bone marrowBreadth of expression: 1 out of 22 libraries express this gene (4.55%)Average CPM:0.63
brainBreadth of expression: 20 out of 759 libraries express this gene (2.64%)Average CPM:4.14
cartilageBreadth of expression: 1 out of 16 libraries express this gene (6.25%)Average CPM:0.92
cerebellumBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:1.13
colonBreadth of expression: 2 out of 930 libraries express this gene (0.22%)Average CPM:14.84
germ cellBreadth of expression: 1 out of 6 libraries express this gene (16.67%)Average CPM:0.13
heartBreadth of expression: 1 out of 26 libraries express this gene (3.85%)Average CPM:0.39
kidneyBreadth of expression: 8 out of 145 libraries express this gene (5.52%)Average CPM:1.90
lungBreadth of expression: 3 out of 334 libraries express this gene (0.90%)Average CPM:3.88
muscleBreadth of expression: 1 out of 83 libraries express this gene (1.20%)Average CPM:0.87
nervousBreadth of expression: 1 out of 21 libraries express this gene (4.76%)Average CPM:0.93
ovaryBreadth of expression: 1 out of 170 libraries express this gene (0.59%)Average CPM:280.58
pancreasBreadth of expression: 2 out of 20 libraries express this gene (10.00%)Average CPM:3.89
parathyroidBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:0.22
prostateBreadth of expression: 5 out of 309 libraries express this gene (1.62%)Average CPM:1.20
skinBreadth of expression: 1 out of 38 libraries express this gene (2.63%)Average CPM:0.43
spleenBreadth of expression: 1 out of 15 libraries express this gene (6.67%)Average CPM:1.73
stomachBreadth of expression: 5 out of 310 libraries express this gene (1.61%)Average CPM:1.30
uncharacterized tissueBreadth of expression: 18 out of 1739 libraries express this gene (1.04%)Average CPM:3.31
whole bodyBreadth of expression: 1 out of 12 libraries express this gene (8.33%)Average CPM:0.56
SAGE (16905870 tags, 305 libraries)
Tissue Breadth ? CPM ?
bloodBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:41.22
brainBreadth of expression: 29 out of 30 libraries express this gene (96.67%)Average CPM:127.54
cerebellumBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:136.51
cervixBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:230.13
colonBreadth of expression: 8 out of 8 libraries express this gene (100.00%)Average CPM:86.60
eyeBreadth of expression: 4 out of 6 libraries express this gene (66.67%)Average CPM:75.15
foreskinBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:102.47
heartBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:11.85
kidneyBreadth of expression: 2 out of 3 libraries express this gene (66.67%)Average CPM:93.64
liverBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:29.91
lungBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:89.74
mammary glandBreadth of expression: 16 out of 20 libraries express this gene (80.00%)Average CPM:97.75
mesothelial tissueBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:198.97
muscleBreadth of expression: 2 out of 2 libraries express this gene (100.00%)Average CPM:74.26
nervousBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:162.39
ovaryBreadth of expression: 7 out of 10 libraries express this gene (70.00%)Average CPM:70.17
pancreasBreadth of expression: 5 out of 8 libraries express this gene (62.50%)Average CPM:91.97
prostateBreadth of expression: 14 out of 14 libraries express this gene (100.00%)Average CPM:102.75
skinBreadth of expression: 3 out of 7 libraries express this gene (42.86%)Average CPM:78.50
stomachBreadth of expression: 4 out of 4 libraries express this gene (100.00%)Average CPM:80.63
uncharacterized tissueBreadth of expression: 16 out of 20 libraries express this gene (80.00%)Average CPM:64.38
vascularBreadth of expression: 3 out of 3 libraries express this gene (100.00%)Average CPM:79.76
EvidenceMutation in Rrenal Tubular Acidosis

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco