Human

Human Prostate Gene DataBase

Name early growth response 1
Symbol EGR1
Aliases TIS8; NGFI-A; KROX-24; ZIF-268; G0S30
Gene Product
  • early growth response 1
Category
  • Mutation in Prostate cancer
UniGeneHs.326035
OMIM128990
Locus1958
SummaryEarly response protein, may function as a transcriptional regulator; has putative zinc finger domains
Gene Ontology
Expression
EST (386 ESTs, 183 libraries)
Tissue ? Frequency ? Count ?
adrenal gland (2/15)0.025 2/17521
blood (2/27)0.036 4/40686
bone (2/13)0.004 2/26211
bone marrow (7/263)0.145 10/38555
brain (5/204)0.004 13/362011
cartilage (3/5)0.008 7/11018
colon (15/853)1.000 38/165626
ear (1/2)0.013 7/12660
esophagus (1/6)0.009 1/3022
germ cell (1/7)0.001 1/57383
head and neck (19/990)0.160 27/79796
heart (2/22)0.001 2/55494
kidney (6/86)0.053 19/132968
liver (2/38)0.005 4/46472
lung (22/312)0.007 86/245386
muscle (3/21)0.005 5/71297
nervous (5/475)0.923 7/43438
ovary (7/144)0.037 13/81880
pancreas (5/33)0.003 10/117255
parathyroid (1/4)0.003 2/19377
placenta (3/342)0.018 4/157762
prostate (16/291)0.034 22/109871
stomach (3/312)0.010 5/129930
testis (3/171)0.003 6/117531
thymus (1/17)0.008 1/5021
thyroid (1/24)0.053 1/6853
uncharacterized tissue (38/1773)0.023 79/713325
uterus (6/212)0.003 7/155110
SAGE (18302841 tags, 353 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.106 3/97046
brain (18/19)0.329 166/3110380
colon (7/8)0.534 78/1364930
eye (6/6)0.998 119/1777486
foreskin (2/2)0.792 5/19256
heart (1/1)0.395 21/674856
kidney (2/2)0.121 5/115792
liver (1/1)0.352 16/334305
lung (1/1)0.391 17/445715
mammary gland (15/19)0.463 212/2304042
muscle (2/2)0.119 6/269353
ovary (7/10)0.516 67/615320
pancreas (7/8)0.528 67/931449
prostate (10/13)0.623 188/1916279
skin (6/7)0.383 13/177607
stomach (2/3)0.479 35/620694
uncharacterized tissue (19/22)1.000 561/3265412
vascular (3/3)0.053 10/262919
SNPrs2294175 (G/C:mrna-utr);  rs6914 (T/C:mrna-utr);  rs1803556 (T/G:mrna-utr);  rs1042197 (A/G:mrna-utr);  rs1042088 (C/T:coding-nonsyn);  
EvidenceMutation in Prostate cancer

© 2002, PGDB, All Rights Reserved.
Department of Urology
Universityof California, San Francisco