Human

Human Prostate Gene DataBase

Name eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD)
Symbol EIF3S3
Aliases EIF3-P40; EIF3-GAMMA
Gene Product
  • eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD)
Category
  • Amplification in Prostate cancer
UniGeneHs.58189
OMIM603912
Locus8667
SummaryTranslation initiation factor 3, subunit 3 (gamma, 40kD); subunit of the complex that stabilizes initiator Met-tRNA binding to 40S subunits
Gene Ontology
Expression
EST (883 ESTs, 259 libraries)
Tissue ? Frequency ? Count ?
adrenal gland (3/15)0.037 4/17521
b cells (1/1)0.028 33/16734
blood (3/27)0.006 12/40686
bone (4/13)0.005 7/26211
bone marrow (5/263)0.002 6/38555
brain (19/204)0.001 51/362011
cartilage (2/5)0.011 4/11018
cervix (2/7)0.051 11/28115
colon (25/853)1.000 115/165626
embryo (4/19)0.002 10/37976
eye (6/33)0.017 39/93836
gall (1/3)0.009 1/2502
germ cell (1/7)0.002 1/57383
head and neck (6/990)0.378 8/79796
heart (3/22)0.010 22/55494
intestine (1/4)0.004 3/11528
kidney (9/86)0.007 25/132968
liver (2/38)0.011 4/46472
lung (16/312)0.005 59/245386
muscle (6/21)0.017 16/71297
nervous (6/475)0.096 8/43438
oral cavity (3/18)0.050 4/44567
ovary (12/144)0.025 30/81880
pancreas (7/33)0.003 25/117255
parathyroid (1/4)0.004 5/19377
placenta (6/342)0.061 44/157762
prostate (10/291)0.001 16/109871
skin (10/31)0.005 55/100815
spleen (3/7)0.012 8/9511
stomach (11/312)0.015 23/129930
testis (8/171)0.039 38/117531
thyroid (1/24)0.081 1/6853
umbilical cord (1/3)0.005 2/6185
uncharacterized tissue (48/1773)0.311 129/713325
uterus (12/212)0.003 62/155110
SAGE (24495848 tags, 466 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.409 8/145569
brain (19/19)0.517 205/5187885
cerebellum (1/1)0.311 6/153840
colon (8/8)0.942 141/2133171
eye (6/6)0.499 66/2393061
foreskin (2/2)0.851 5/19256
heart (1/1)0.646 19/421785
kidney (2/2)0.602 13/157649
liver (1/1)0.185 5/200583
lung (1/1)0.899 26/624001
mammary gland (19/19)0.805 215/2876725
muscle (2/2)0.388 14/323162
ovary (9/10)1.000 86/793375
pancreas (8/8)0.710 68/823341
prostate (13/13)0.905 210/2109959
skin (7/7)0.671 23/216152
stomach (3/3)0.632 44/1105995
uncharacterized tissue (21/22)0.920 192/3869246
vascular (3/3)0.805 50/941093
SNPrs1529945 (C/T:intron);  rs2366 (T/G:intron);  rs10054 (G/C:mrna-utr);  rs1436767 (A/G:intron);  rs2278491 (T/C:locus-region);  rs1317271 (A/T:intron);  rs1347626 (C/T:locus-region);  rs1804926 (A/C:coding-nonsyn);  rs1343663 (C/T:intron);  rs1865889 (A/G:intron);  
EvidenceAmplification in Prostate cancer

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Department of Urology
Universityof California, San Francisco