| Name | G antigen, family C, 1 |
| Symbol | GAGEC1 |
| Aliases | JM27; PAGE4; GAGE-9; PAGE-1; PAGE-4; JM27 protein; prostate-associated gene protein 4 |
| Gene Product | |
| Category | - Over expression in Prostate cancer
- Over expression in Normal prostate
|
| UniGene | Hs.95420 |
| OMIM | 300287 |
| Locus | 9506 |
| Summary | This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens. |
| Expression | | EST (70 ESTs, 24 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/27) |  | 1/40686 |
| heart (1/22) | | 3/55494 |
| placenta (11/342) | | 32/157762 |
| prostate (5/291) |  | 17/109871 |
| uncharacterized tissue (6/1773) | | 17/713325 |
|
| SAGE (1891017 tags, 28 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| brain (5/19) | | 7/448576 |
| colon (1/8) | | 5/61667 |
| eye (2/6) | | 5/317956 |
| heart (1/1) | | 1/84357 |
| mammary gland (3/19) | | 3/183264 |
| ovary (1/10) | | 1/48552 |
| prostate (4/13) | | 34/260013 |
| stomach (2/3) | | 2/136465 |
| uncharacterized tissue (3/22) | | 7/350167 |
|
|
| SNP | rs2280892 (A/G:mrna-utr); rs1802956 (T/C:coding-nonsyn); |
| Evidence | Over expression in Prostate cancer
Over expression in Normal prostate
|
