Human

Human Prostate Gene DataBase

Name glutathione S-transferase M1
Symbol GSTM1
Aliases MU; GST1; H-B
Gene Product
  • glutathione S-transferase M1
Category
  • Polymorphism in Prostate cancer
UniGeneHs.301961
OMIM138350
Locus2944
SummaryMember of the mu class of glutathione S-transferases; have activity towards trans-stilbene oxide
Gene Ontology
Expression
EST (60 ESTs, 42 libraries)
Tissue ? Frequency ? Count ?
bone (1/13)0.011 1/26211
brain (6/204)0.052 14/362011
head and neck (2/990)0.383 2/79796
heart (1/22)0.018 1/55494
kidney (1/86)0.044 1/132968
liver (2/38)0.006 3/46472
lung (4/312)0.278 4/245386
muscle (1/21)0.004 1/71297
nervous (1/475)0.272 1/43438
ovary (3/144)0.178 3/81880
pancreas (1/33)0.014 3/117255
prostate (1/291)0.043 1/109871
spleen (1/7)0.009 1/9511
stomach (2/312)0.447 3/129930
testis (5/171)0.280 6/117531
uncharacterized tissue (9/1773)1.000 12/713325
uterus (1/212)0.074 3/155110
SAGE (7118628 tags, 136 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.101 1/48523
brain (16/19)0.445 88/1811211
cerebellum (1/1)0.095 1/51280
colon (4/8)0.209 8/339562
eye (6/6)0.720 42/709079
foreskin (1/2)1.000 2/9759
heart (1/1)0.521 9/84357
kidney (1/2)0.291 3/125571
liver (1/1)0.146 2/66861
lung (1/1)0.274 3/178286
mammary gland (8/19)0.411 32/738563
muscle (2/2)0.838 19/215456
ovary (5/10)0.245 9/246685
pancreas (6/8)0.233 11/245551
prostate (8/13)0.391 28/747114
skin (3/7)0.475 4/55672
stomach (1/3)0.579 3/25302
uncharacterized tissue (15/22)0.509 74/1133288
vascular (2/3)0.245 8/286508
SNPrs1065410 (G/C:coding-nonsyn);  rs421547 (C/T:locus-region);  rs1296954 (G/A:locus-region);  rs412543 (C/G:locus-region);  rs1758109 (A/G:locus-region);  rs674787 (G/A:locus-region);  rs679005 (A/T:locus-region);  rs674761 (A/G:locus-region);  rs412302 (C/T:locus-region);  rs1292096 (T/C:locus-region);  rs756637 (C/T:intron);  rs1634252 (A/G:locus-region);  rs2239892 (C/T:intron);  rs737497 (A/G:intron);  rs1056806 (T/C:coding-nonsyn);  rs2071487 (T/C:coding-nonsyn);  rs414673 (A/G:locus-region);  rs679035 (C/T:locus-region);  
EvidencePolymorphism in Prostate cancer

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Department of Urology
Universityof California, San Francisco