Human

Human Prostate Gene DataBase

Name Ras association (RalGDS/AF-6) domain family 1
Symbol RASSF1
Aliases 123F2; RDA32; NORE2A; REH3P21; candidate tumor suppressor similar to rat Maxp1 and ras effector nore1
Gene Product
  • Ras association (RalGDS/AF-6) domain family 1
Category
  • Methylation in Prostate cancer
UniGeneHs.26931
OMIM605082
Locus11186
SummaryRas association (RalGDS/AF-6) domain family 1; highly similar to a region of murine Nore1
Expression
EST (142 ESTs, 77 libraries)
Tissue ? Frequency ? Count ?
adrenal gland (2/15)0.569 3/17521
blood (1/27)0.011 1/40686
bone marrow (2/263)0.904 5/38555
brain (10/204)0.008 26/362011
cervix (3/7)0.012 4/28115
colon (4/853)1.000 9/165626
embryo (1/19)0.049 1/37976
esophagus (1/6)0.048 2/3022
eye (3/33)0.048 6/93836
heart (1/22)0.005 1/55494
kidney (4/86)0.068 6/132968
liver (1/38)0.008 1/46472
lung (3/312)0.034 5/245386
mammary gland (1/1)0.029 1/2313
nervous (1/475)0.027 2/43438
oral cavity (1/18)0.002 1/44567
ovary (2/144)0.971 2/81880
pancreas (4/33)0.011 5/117255
placenta (4/342)0.004 17/157762
prostate (4/291)0.011 4/109871
skin (1/31)0.006 2/100815
stomach (3/312)0.025 8/129930
t cells (1/2)0.041 2/4729
testis (2/171)0.027 3/117531
uncharacterized tissue (14/1773)0.010 21/713325
uterus (3/212)0.071 4/155110
SAGE (15726809 tags, 333 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.920 42/145569
brain (19/19)0.575 634/2861854
cerebellum (1/1)0.492 25/153840
colon (8/8)0.531 219/1445762
eye (5/6)0.676 295/807558
foreskin (2/2)0.315 6/19256
heart (1/1)0.684 57/253071
kidney (2/2)0.888 67/189727
liver (1/1)0.592 39/133722
lung (1/1)0.863 76/267429
mammary gland (19/19)1.000 693/2342127
muscle (2/2)0.546 56/269309
ovary (10/10)0.633 170/914238
pancreas (7/8)0.404 97/675303
prostate (13/13)0.615 293/1874419
skin (7/7)0.583 60/141049
stomach (3/3)0.550 78/393967
uncharacterized tissue (22/22)0.781 687/2278356
vascular (3/3)0.450 77/560253
SNPrs2073497 (A/G:intron);  rs2236947 (C/A:intron);  rs1046468 (G/A:mrna-utr);  
EvidenceMethylation in Prostate cancer

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Department of Urology
Universityof California, San Francisco